Deca Durabolin (Nandrolone Decanoate)

Published Oct 20, 2016 by:
Dan Chaiet Author
Biomedical Science
Biomedical Science Graduate. After completing the educational and research requirements for a PhD in Biomedical Science, Dan is currently studying at York University in Toronto, Ontario, Canada and has less than a year before joining the Medical Board becoming an MD and qualified Doctor. Dan's educational emphasis is on performance enhancement drugs (PEDs), endocrinology, nutritional supplements and strategies for health, fat reduction, anti-ageing, muscle growth, disease control and vaccinations. Dan has had an interest in learning and writing about steroid use for over 15 years.

Are you interested in improving your performance? Do you want to take your athletic career to the next level? For millions of athletes the world over, an entire market of supplements exist that provide myriad benefits for performance. One of the most recognized performance enhancing supplements is Deca Durabolin. Below we review everything you need to know about this drug, its performance enhancer effects, negative side effects and how to best use Deca-Durabolin.

Deca Durabolin: Brief Description

One of the best received anabolic steroids on the market to date; Deca Durabolin has made a name for itself. Attaching to the large Decanoate ester, Deca Durabolin is made up of the Nandrolone steroid hormone. It is among the most widely used anabolic steroids among athletes looking to improve their performance. Providing incredible benefits during the off season, it is favored in part for it’s therapeutic benefits. With years of anabolic steroid controversy, the actual affects of Deca Durabolin have been blurred with fears and anxieties regarding things like ‘roid rage.’ This is in part due to its connection to the sex hormone testosterone and various misinformation that exists around what it can do.

Nandrolone (the steroid hormone that makes up Deca Durabolin) first appeared in the 1960’s with the intent for commercial use. Put under the trade name Deca Durabolin, it has gone through numerous versions and renaming periods over time. Despite this, Deca Durabolin remains the most recognizable name for the drug out there. Due to fears about what it can do, the US has limited access to the drug. Despite that, Deca Durabolin remains to this day a popular therapeutic treatment that is beloved for the range of things it can aid in.

Deca Durabolin Organon
Deca Durabolin Organon

Deca Durabolin Chemical Characteristics & Properties

The drug is a 19-nortestosterone anabolic androgenic steroid. Also referred to as 19-nor, Deca Durabolin is classified based on its molecular chain, where it is lacking a carbon atom on its 19th position. Representing an incredibly small change in structure, the effects could not be more pronounced. A unique steroid, it is now capable of attaching to a Nandrolone base, which attaches it to the large Decanoate ester. This slows down the release quite a bit making it a very slow acting ester. Making frequent injections a thing of the past, the Deca Durabolin requires a shot only every 2-3 weeks instead of the daily or weekly requirements of other testosterone supplements. A sharp increase in Nandrolone released by the body is not uncommon in the first few days after beginning a Deca Durabolin regime.


Slightly greater than testosterone proper, Deca Durabolin has a higher potent anabolic rating. Despite this, the overall androgenic rating of Deca Durabolin is only 37 (testosterone is 100.) Reducing to DHN or dihydronandrolone, Deca Durabolin is much slower reacting and conversely easiest to tolerate anabolic steroids out there. It owes its success in part to its very low estrogenic activity. While Deca Durabolin can aromatize in the blood, it does so at a whopping 20% compared to testosterone. Be aware that despite this, you may still need to be aware of its progestin nature. With that in mind, we will discuss the potential side effects later in this article.

Uses In Sports

So how does Deca Durabolin aid your body chemically? Well, like a few other anabolic steroids out there, this drug enhances your body’s protein synthesis and promotes IGF-1 output. In addition, it aids in inhibiting glucocorticoid hormones. The result of this is increased nitrogen retention in the muscles, stronger and bigger muscles, and increased energy. As muscle tissue is approximately 16% nitrogen and Deca Durabolin aids in additional muscle growth, you will have to be sure that your diet has enough protein in it to restore nitrogen levels or risk muscle wasting.

How is Deca Durabolin different than other anabolic steroids? There are two ways that Deca Durabolin is different. The first thing is that Deca Durabolin will increase bone mineral content. The second thing is that Deca Durabolin will enhance the collagen synthesis in the body. These traits ensure improved joint relief among athletes, as well as improving red blood cell counts.

Uses Outside Sports

An additional benefit of Deca Durabolin is that it is seen as an excellent anabolic steroid for those who are suffering from muscle wasting diseases. Improving fatigue and geriatric weakness, Deca Durabolin has been used positively for anemia as well. Great for those who have experienced burns, those who have had breast cancer, and those who have ulcers, Deca Durabolin does provide benefits for the body outside of bodybuilding and athletic competitions. This is especially seen in Deca Durabolin’s ability to treat osteoporosis through increasing bone mineral content and collagen synthesis. As you might expect, Deca Durabolin has also seen use in helping those with HIV. Finally, it has even been suggested that Deca Durabolin can be used for it’s positive anti-aging qualities.

Deca Durabolin Effects

Let’s take a moment to go into further details about the beneficial performance and therapeutic affects that Deca Durabolin provides. The truth is, Deca Durabolin is poorly understood. Some individuals will only consider Deca Durabolin a bulking steroid, forgetting or glossing over the other beneficial and therapeutic qualities. In addition, some bodybuilders even use it during cutting phases. The only way to understand what Deca Durabolin is to drop the viewpoint that anabolic steroids can only enhance lean muscle tissue. Considering this criteria only, there are better options out there. However, when you take in the full range of health benefits, you will see why Deca Durabolin is superior in many ways.

1. Offseason Bulking Steroid

Deca Durabolin is commonly and successfully used as an offseason bulking steroid. It is great for improving lean mass slowly over time. A large ester steroid, it is in no way fast acting. That being said, the fact that it is long lasting will mean better improvements over time with fewer injections required. Fairly easy to control, you will see strength increases slowly accumulating over use.

2. Therapeutic Effects

As mentioned above, Deca Durabolin provides numerous therapeutic qualities that make it great for use during the off season. Along with new growth and less body fat, the steroid will aid in recovery. Many athletes who would benefit from Deca Durabolin would also benefit from not gaining additional muscle mass. Very low doses are capable of providing this relief for athletes. Be aware that Deca Durabolin is in no way an opiate and cannot stop pain. Rather, it deals directly with the source of several highly specific types of pain and aids your body in recovery. As a result, it is popular during cutting phases in low doses. While it will help harden muscles, it is none-the-less a good option for cutting phases as well.

3. Metabolism

It is well known that anabolic steroids (including Deca Durabolin) are great for shedding body fat. This is done by increasing your metabolic rate. In addition, by adding more muscle mass, your body will have to spend more energy feeding that muscle to keep it active. As off season often included added calories, Deca Durabolin can be just what you are looking for to keep your body in the right condition.

Deca Durabolin: Side Effects

Not all affects of Deca Durabolin are positive. When used incorrectly or by someone whose physiology does not react well with the drug, there can be side effects. For men, Deca Durabolin is generally safe in higher doses while for women the rates should be kept lower. Safely taking Deca Durabolin will require knowing what side effects to look out for and changing your prescription to reduce side effects while providing the most amount of benefits. To help you quickly navigate potential side effects, below are listed what can happen according to category. Let’s begin!

1. Estrogenic Side Effects

No doubt the most feared, all anabolic steroids run some risk of estrogenic side effects. Deca Durabolin is pretty low on the risk level when it comes to these drugs. It does carry a slight aromatizing nature, which is far below the average. This is good, because as estrogen levels increase, feminizing side effects like gynecomastia can occur. Deca Durabolin does carry the risk of binding with progesterone receptors, which stimulate estrogenic effects in the body. So, while Deca Durabolin has a very low risk of feminizing in one direction, it carries a much higher risk through a different chemical process.


How do you protect yourself against this? Well, when taking Deca Durabolin you can also take ant-estrogen medications to counter the results. Things like Nolvadex and Arimidex are popular choices. Both approach limiting the effects of estrogen different and will have different side effects on your health worth considering. Even with side effects though it is still worth pursuing either of these options. Gynecomastia is a particularly big problem due to how the imbalance between estrogen and progesterone is what leads to gynecomastia. So, by keeping your hormone levels regulated, you reduce the risk of potential unwanted growth.

2. Androgenic Side Effects

While Deca Durabolin can produce androgenic side effects in men, it is relatively uncommon unless you are taking a significant amount of the drug. For example, things like hair loss, acne, and male pattern baldness are all possible. If you already have a genetic predisposition for these things, then expect to potentially suffer from it while you are taking the medication. Because Deca Durabolin breaks apart into DHN and not DHT, there are less effects on scalp hair and the overall androgenic results are less frequent and intense.

If you are interested in stopping androgenic side effects from occuring, then you may think to use a 5-alpha reductase inhibitor. Do not do this. Due to the chemical composition of the drug, doing this will have the opposite effect and increase the risk of androgenic side effects.

Side effects for women virilization effects. Clitoral enlargement, deepening vocal chords, and body hair growth are all symptoms that can occur to women who take too much of the drug. It takes much lower doses of the drug to use it without seeing the virilization effects. While it is possible, it will require careful monitoring. Once the side effects are noticed, immediately stop taking it. Ignored symptoms run the risk of becoming permanent.

3. Cardiovascular Side Effects

Out of every potential side effect of Deca Durabolin, this is the one that you will want to keep the closest eye on. Deca Durabolin can have a negative impact on your cholesterol level. The HDL and LDL ratios in your body may be out of whack as you take Deca Durabolin. HDL in particular will be strongly impacted to a degree that is still less intense than most oral steroids. Stopping cardiovascular side effects will require living a lifestyle that is friendly to reducing cholesterol rates. Diet and exercise are critical. Foods that are rich in omega fatty acids will play a particularly important role in your health.

testostrone-suppression4. Testosterone Side Effects

Anabolic steroids suppress the body’s natural production of testosterone. Deca Durabolin is no different. Expect a great deal of reduction of naturally occuring testosterone when you take Deca Durabolin. Among the most extreme drugs out there in terms of loss to naturally occuring testosterone during use, you will need to take a testosterone supplement in order to restore yourself to the correct levels. Exogenous testosterone will lower any conditions and symptoms associated with a sudden loss of testosterone in the system. If nothing else, not dealing with your lack of natural testosterone production will be incredibly unhealthy.

While Deca Durabolin will limit natural testosterone production during its use, eliminating the drug from your system will see natural testosterone levels return. It is not uncommon for people to enter a post cycle therapy to improve the recovery process. Expect the recovery to take several months and do not take other anabolic steroids while you wait for levels to return to normal.

Deca Durabolin is frequently advertised as a safe anabolic steroid that will not permanently harm naturally occuring testosterone production. For natural recovery to occur, you will have to have begun the process with a normal level of testosterone in your body. If you have existing low testosterone, then stopping Deca Durabolin will not magically return it to a higher number after it has left your system. Keep your expectations grounded and give your body the time it needs to fully recover after a cycle is complete.

5. Hepatotoxicity Side Effects

Because Deca Durabolin is classified as an anabolic steroid, many people fear that it will somehow cause damage to the liver or other vital organs. This is not true when it comes to Deca-Durabolin. Deca Durabolin is non toxic and will not present stress or damage to your organs.

Administering Deca Durabolin

1. Administration Frequency

So, how often should you self administer Deca Durabolin? Good question. As we’ve covered above, Deca Durabolin is a slow acting steroid that will not need to be frequently injected. When used in therapeutic treatment plans, smaller doses are used and the lasting time is pretty long compared to other anabolic steroids. It should be administered once every 2-4 weeks. Most people will administer between 3 to 4 weeks. If you are using Deca Durabolin to treat conditions that are not related to performance and bodybuilding, then the frequency will be different. For example, those who are dealing with anemia will inject around once a week to decrease injection volume.

2. Deca-Durabolin Dosages

How much will be in each injection? 100mg is typically used for therapeutic treatments. 100-200mg per week is common for those treating anemia. 100mg per week is the standard starting point for athletes looking for relief. Many end up moving up to 200mg a week once they become settled. Some may go even further for anabolic gains and up the amount to 300 and even 400mg a week. While men can tolerate levels up to 600mg a week, the results will significantly begin to decline the closer and closer you get to that number. Remember, the more of it you take, the greater the risk of things like adverse side effects. For women, it is recommended that they take 50mg a week. Some women can handle up to 100mg.

3. Duration & Off Time

How long should you maintain dosage and how long should your recovery period be? Deca Durabolin should be used for a period of time that is at least 8 weeks. Being extremely slow acting, Deca Durabolin will still be in your body for several weeks after. Men typically use it for 10-12 weeks at a time. While up to 16 weeks is seen for hardcore bodybuilders, it is not recommended for those new to go anywhere near 16 weeks of use. For women, expect to administer the drug for around 3 to 4 weeks before taking a break.

Deca Durabolin Availability

US pharmacies do not manufacture Deca Durabolin on account of laws that prohibit the sales of anabolic steroids in the states. That being said, you can legitimately obtain Deca Durabolin from pharmaceutical companies outside the country as well as the black market. Any Nandrolone that you find in the United States that you can trust will be imported from a different country. If you go the root of the black market, then know that Nandrolone is frequently found in such places all over the world. Be aware that counterfeit products do exist and that you should be aware of it. Also know that Greek Normal Hellas and Alpha Pharma’s Nandrobolin are among some of the brands that you can trust.

Legality: A Warning About Online Purchases

The majority of people will end up purchasing their Deca Durabolin online. This is because it is easily accessible, available to be shipped, and inexpensive. There are many suppliers around the world and competition helps to keep costs of the drug down. Be aware that living in the United States means that purchasing Deca Durabolin online is illegal. It is a violation of the Steroid Control Act of 1990 and is considered a violation of federal law. People caught will be prosecuted under the law. Why is the US so harsh? Well, many steroids are classified as schedule drugs that are monitored by the government. So, in the eyes of the law, there is little difference between something like Deca Durabolin and cocaine. Before purchasing Deca Durabolin, be aware of what laws exist and how they may affect you, in your own country. The more you know, the safer you can approach the world of anabolic steroids and understand the risks before buying steroids.

Deca Durabolin Structural Information

  • Nandrolone Base + Decanoate Ester
  • 19-nor-androst-4-en-3-one-17beta-ol
  •  Molecular Base Weight of Deca Durabolin is 274.4022
  • Molecular Weight (ester of Deca Durabolin is 172.2668
  • Formula (base): C18 H26 O2
  • Formula (ester):C10 H20 O2
  • Melting Point of Deca Durabolin Base is 122-124C
  • Melting Point of Deca Durabolin Ester is 31 – 32 C
  • Male Dosage: 200-600mgs/wk
  • Female Dosage: 50-100mgs/wk
  • Active For 18 days
  • Can Be Detected Up To18 Months
Dan Chaiet Author
Biomedical Science
Biomedical Science Graduate. After completing the educational and research requirements for a PhD in Biomedical Science, Dan is currently studying at York University in Toronto, Ontario, Canada and has less than a year before joining the Medical Board becoming an MD and qualified Doctor. Dan’s educational emphasis is on performance enhancement drugs (PEDs), endocrinology, nutritional supplements and strategies for health, fat reduction, anti-ageing, muscle growth, disease control and vaccinations. Dan has had an interest in learning and writing about steroid use for over 15 years.